Oral / Poster Presentation File
1department of physical education and sport science,payame noor university,tehran,iran
2department of exercise physiology ,faculty of sport science, university of mazandaran,babolsar,iran
Objective: The aim of this study was to evaluate the KATP response of ATP-sensitive potassium channels to the protection of heart tissue in male rats after eight weeks of resistance training.
Methodology: The present study was an experimental study consisting of 10 healthy male Wistar rats with a mean weight of 150 70 70 which were randomly divided into control and resistance training groups. The resistance training group performed the training protocol for 8 weeks. For immunohistochemical tests, the heart tissue was measured and the level of potassium channel proteins (KIR6.2, SUR) in the left ventricle of the tissue was measured. Independent t-test was used to analyze the data. Significance level was considered less than 0.05.
Results: After 8 weeks of resistance training, it was shown that the expression of potassium channel proteins (KIR6.2, SUR) in the resistance training group was higher than the control group (P = 0.001).
Conclusion: It seems that resistance training by manipulating the ATP mechanism increases the number of ATP-sensitive potassium channels in the heart tissue, which ultimately leads to a reduction in tissue damage
