| The effects of Circuit resistance training on serum CTRP5 and CTRP12 in obese men |
| Paper ID : 1520-SSRC-13TH |
| Authors |
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salah abroukaman *, najmadin espandar, Mohammad reza zolfaghari, Akbar Nuri Habashi, jalal shirzad, Abobaker hassanzadeh گروه فیزیولوژی ورزشی و حرکات اصلاحی، دانشکده تربیت بدنی، دانشگاه ارومیه، ارومیه، ایران |
| Abstract |
| BACKGROUND: Obesity contributes to a state of chronic low-grade inflammation, with altered production and function of adipokines. Exercise health benefits are partly mediated by exertional changes in several adipokines. Secreted C1q/TNF-related proteins (CTRPs) are one such group of regulators that regulate glucose, insulin sensitivity and fat metabolism in peripheral tissues and modulate inflammation in adipose tissue. CTRP-5 and CTRP12 are a promising target for the treatment of chronic low-grade inflammation-related diseases that opening up a new therapeutic avenue for the treatment of obesity. Aim: The aim of this study was to investigate effect of Circuit resistance training (CRT) on CTRP5, CTRP12 on modulate inflammation in adipose tissue. Materials and Methods: In this study, 22 obese man in the age range of 23-32 years old randomly divided into two groups including one groups of resistance training (n=11) and one control group (n=11). Exercises in CRT protocol included back squats, lat pulldown, leg press, chest press, leg extension, leg curls lateral raise, standing calf raise, biceps curl, triceps push down, and abdominal crunch. the CRT protocol included three circuits of 10 exercises, at an intensity of 50% of 1-RM, 14 repetitions with a minimum rest (< 15 s) between exercises and 3 min rest between sets. Blood samples were taken before and 72 hours after the last training session and were used to analyze the factors. For comparison between groups, two-way analysis of variance and Bonferroni post hoc test were used and for intragroup changes T test was used at a significant level (P <0.05). Results: After 12 weeks, the results showed that CTRP-5 (p <0.001) and CTRP12 (p <0.001) had increase compared to controls. Conclusion: This results demonstrated that after 12 weeks, CTRP5 and CTRP12 levels increased. So CTRP5 and CTRP12 are novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. |
| Keywords |
| Inflammation, Obesity, Adipose tissue |
| Status: Abstract Accepted (Poster Presentation) |
