Effect of high intensity interval training on oxidative stress status and Total antioxidant capacity in Liver tissue of male rats during puberty |
Paper ID : 1806-SSRC-13TH |
Authors |
parisa abdollahi *1, Ahmad Rahmani2, Leila Youzbashi3 1Department of Sport Science, Faculty of ,Humanities, University of Zanjan, Iran 2Department of Sport Science, Faculty of Humanities, University of Zanjan, Iran 3Department of Sport Sciences, Faculty of Humanities, University of Zanjan, Zanjan, Iran |
Abstract |
Introduction: Increasing participation of children and adolescents in strenuous exercise is associated with the prevalence of sports injuries in young athletes. Intense physical activity can elevate the production of reactive oxygen species in vital organs such as the liver and causes oxidative stress. However, little is known about the effect of HIIT on oxidative stress in children and teens. This study aimed to investigate the effect of high intensity interval training on oxidative stress of liver tissue in immature male rats. Material and methods: Sixteen male Wistar rats (22-day, 60 ± 63 g) after one week of familiarization, were divided randomly into control and HIIT groups. Training protocol included 4 weeks (6 sessions/w) of treadmill running. HIIT protocol included one-minute of intervals with the specified speed and 2-3 minutes active rest between the intervals. Running speed was started with 16-22 m/min at the first week, and reached to 36-40 m/min at the last week. Forty-eight h after the last training session, performance was measured by the exhaustive endurance test. Animals were sacrificed 24 h after the end of the performance test. The liver tissue was removed and feezed at -80 ◦C. Malondialdehyde (MDA) and Total antioxidant capacity (TAC) levels were measured by Randox kit (England). Data were analyzed using Independent-sample T-test. The statistical significance was set at p≤0.05. Results: HIIT group showed a non-significant decrease (46%) in the MDA level compared to the control group (P= 0.077). Also, there were no statistical differences in liver TAC levels among groups (P= 0.938). Conclusion: HIIT may reduce oxidative stress in liver tissue during adolescence period. So, it can be administered for immature athletes. However, more research is needed in this area. |
Keywords |
Keywords: "High Intensity Interval Training", "Malondialdehyde", "Total Antioxidant Capacity", "liver" |
Status: Abstract Accepted (Poster Presentation) |